An acute condition in which the gallbladder becomes inflamed and swollen because the flow of bile into the duodenum is blocked by gallstones is biliary colic – intense pain in the upper right abdomen or between shoulders, indigestion (especially after fatty food), and nausea (with or without vomiting). If left untreated, the condition can lead to jaundice and occasionally, if the gallbladder bursts, to peritonitis. If the site of pain is as described above, and pain persists for more than 3 hours, consult your doctor if there is no improvement in 2 hours.